HomeResearchPublicationsLab MembersPositionsContact UsFundingLinks

Publications

 
S. Sarvan*, V. Avdic*, V. Tremblay*, C-P. Chaturvedi, P. Zhang, S. Lanouette, A. Blais, J.S. Brunzelle, M. Brand & J-F. Couture. Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain. Nature Structural and Molecular Biology, Epub ahead of print June 5, 2011
* equal contribution

Abstract link

 
 
L. Guevel, J.R. Lavoie, C. Perez-Iratxeta, K. Rouger, L. Dubreil, M. Feron, S. Talon M. Brand* & L. Megeney*. Quantitative proteomic analysis of dystrophic dog muscle. Journal of Proteome Research 10 (5): 2465-2478, 2011
*share equal contribution as senior authors

Abstract link

 
 
C.G. Palii*, C. Perez-Iratxeta*, Z. Yao, Y. Cao, F. Dai, J. Davison, H. Atkins, D. Allan, F.J. Dilworth, R. Gentleman, S.J. Tapscott & M. Brand. Differential genomic targeting of the transcription factor TAL1 in alternate hematopoietic lineages. The EMBO Journal  30 (3): 494-509, 2011 (Epub Dec 21, 2010)
*equal contribution

pdf download

Supplementary Tables

 
 
C.G. Palii, R. Pasha & M. Brand. Lentiviral-mediated knockdown during ex vivo erythropoiesis of human hematopoietic stem cells. Journal of Visualized Experiments  doi: 10.3791/2813. J Vis Exp. 53, 2011

Click here to see the video article

 
 
A.M. Hosey, C-P Chaturvedi & M. Brand. Crosstalk between histone modifications maintains the developmental pattern of gene expression on a tissue-specific locus.
Epigenetics 5 (4):273-281, 2010

pdf download

 
S. Seenundun*, S. Rampalli*, Q.C. Liu*, A. Aziz, C. Palii, S. Hong, A. Blais, M. Brand, K. Ge & F.J. Dilworth. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. The EMBO Journal 29(8):1401-1411, 2010
*equal contribution

pdf download

 
C-P. Chaturvedi*, A.M. Hosey*, C. Palii, C. Perez-Iratxeta, Y. Nakatani, J.A. Ranish, F.J. Dilworth & M. Brand. Dual role for the methyltransferase G9a in the maintenance of ß-globin gene transcription in adult erythroid cells. Proceedings of the National Academy of Sciences, 106 (43): 18303-18308, 2009
*equal contribution

download pdf

 
A.M. Hosey & M. Brand. Chromatin-mediated spreading on active genes. Nature Structural and Molecular Biology 16 (1): 11-13, 2009

Abstract link

 
M. Brand, S. Rampalli, C-P. Chaturvedi, and F.J. Dilworth. Analysis of epigenetic modifications of chromatin at specific gene loci by native chromatin immunoprecipitation (N-ChIP) of nucleosomes isolated using hydroxyapatite chromatography. Nature Protocols 3 (3): 398-409, 2008

download pdf

 
C. Demers, C.P. Chaturvedi, J. A. Ranish, G. Juban, P. Lai, F. Morle, R. Aebersold, F. Dilworth, M. Groudine and M. Brand. Activator-mediated Recruitment of the MLL2 Methyltransferase Complex to the ß-globin Locus.  Molecular Cell, 27: 573-584, 2007

download pdf

 
S. Rampalli, L. Li, E. Mak, K. Ge, M. Brand, S.J. Tapscott, and F.J. Dilworth. p38 MAPK signaling pathway regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation. Nature Structural and Molecular Biology 14: 1150-1156, 2007

download pdf

 
A. Kim, S. Song, M. Brand and A. Dean. Nucleosome and transcription activator antagonism at human ß-globin locus control region DNase I hypersensitive sites. Nucleic Acids Research 35 (17): 5831-5838, 2007

download pdf

 
J.A Ranish, M. Brand and R. Aebersold. Using stable isotope tagging and MS to characterize protein complexes and to detect changes in their composition. Methods Mol Biol. 359:17-35, 2007

download pdf

 
M. Brand, J. A. Ranish, N. T. Kummer, J. Hamilton, K. Igarashi, C. Francastel, T. Chi, G. R. Crabtree, R. Aebersold and M. Groudine. Dynamic changes in transcription factors complexes during erythroid differentiation revealed by quantitative proteomics. Nature Structural and Molecular Biology, 11 (1): 73-80, 2004

download pdf

 
J. Sun, M. Brand, Y. Zenke, S. Tashiro, M. Groudine and K. Igarashi. Heme regulates dynamics of Bach1 and NF-E2-related factors in the Maf transcription factor network. Proceedings of the National Academy of Sciences, 101 (6): 1461-1466, 2004

download pdf

 
N. Cavusoglu,  M. Brand, L. Tora and A. Van Dorsselaer. Novel subunits of the TATA Binding Protein Free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one dimensional gel electrophoresis. Proteomics, 3 (2): 217-223, 2003

download pdf

 
S. Hardy*, M. Brand*, G. Mittler, J. Yanagisawa, S. Kato, M. Meisterernst and L. Tora. TATA-binding protein-Free TAF-containing complex (TFTC) and p300 are both required for efficient transcriptional activation. Journal of Biological Chemistry 277: 32875-32882, 2002
*equal contribution

download pdf

 
Y. G. Gangloff, J. C. Pointud, S. Thuault, L. Carre, C. Romier, S. Muratoglu, M. Brand, L. Tora, J. L. Couderc and I. Davidson. The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger. Molecular and Cellular Biology 21 (15): 5109-51021, 2001

download pdf

 
M. Brand, J. G. Moggs, M. Oulad-Abdelghani, F. Lejeune, F. J. Dilworth, J. Stevenin, G. Almouzni and L. Tora. UV-damaged DNA binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. The EMBO Journal 20 (12): 3187-3196, 2001

download pdf

 
M. Brand*, C. Leurent*, V. Mallouh, L. Tora and P. Schultz. Three dimensional structures of the TAFII-containing complexes TFIID and TFTC. Science 286: 2151-2153, 1999
*equal contribution

download pdf

 
M. Brand, K. Yamamoto, A. Staub and L.Tora. Identification of TFTC subunits suggests a role in nucleosome acetylation and signal transduction. Journal of Biological Chemistry 274 (26): 18285-18289, 1999

download pdf

 
L. Tora, M. Brand, E. Wieczorek and D. Metzger. The role of TAFII30-containing complexes in vertebrate gene regulation. in: Human Frontier Workshop VII on "Transcription Regulation in Eukaryotes" Eds. P. Chambon, R.D. Kornberg, T. Fukasawa and C. Coath. HFSP, Strasbourg, France. pp. 162-170, 1999

download pdf

 
E. Wieczorek*, M. Brand*, X. Jacq and L. Tora. Function of TAFII-containing complex without TBP in transcription by RNA polymerase II. Nature  393: 187-191, 1998
*equal contribution

download pdf